Joint PIs

2022-06 ~ Present      Professor, School of Life Sciences Fudan University, Shanghai, China
2017-07 ~ 2022-06     Associate Professor, School of Life Sciences Fudan University, Shanghai, China
2014-01 ~ 2017-06     Postdoctoral fellow, Harvard T.H. Chan School of Public Health, Department of Nutrition, Boston, MA, US
2010-08 ~ 2013-12     Ph.D. Philosophy, Epidemiology, UTHealth, Houston, TX, US                                          
2008-08 ~ 2010-05     M.S. Public Health, Epidemiology, Emory University, Atlanta, GA, US                          
2005-09 ~ 2008-07     M.S. Internal Medicine (specialized in Cardiology), Fudan University, Shanghai Medical School, Shanghai, China
2000-09 ~ 2005-07     B.M. Clinical Medicine, Capital Medical University, Beijing, China

My research is focused on the role of the gut microbiome and related metabolites in the dietary modulation of risk in cardiometabolic diseases.

1.    Yuxiang Dai, Zhonghan Sun, Yan Zheng*, Junbo Ge*. Recent advances in the gut microbiome and microbial metabolites alterations of coronary artery disease. Science Bulletin 2023 Mar 30;68(6):549-552.
2.    Qinmin Huang#, Xiaofeng Zhou#, Chuqi Zhang, Liyan Huang, Qi Wang, Qinsheng Chen, Huiru Tang, Jingchun Luo, Zhengyuan Wang, Changzheng Yuan*, Yan Zheng*. Validity and Reproducibility of Dietary Measurements Assessed by a Semiquantitative Food Frequency Questionnaire among Chinese Healthy Adults. Nutrients. 2023, 15(3), 545.
3.    Zhonghan Sun#, Xiong-Fei Pan#, Xiao Li, Limiao Jiang, Ping Hu, Yi Wang, Yi Ye, Ping Wu, Bin Zhao, Jianguo Xu, Mengmeng Kong, Yanni Pu, Manying Zhao, Jianying Hu, Jinfeng Wang, Guo-Chong Chen, Changzheng Yuan, Yongfu Yu, Xiang Gao, Fangqing Zhao, An Pan*, Yan Zheng*. The Gut Microbiome Dynamically Associates with Host Glucose Metabolism throughout Pregnancy: Longitudinal Findings from a Matched Case-control Study of Gestational Diabetes Mellitus. Advanced Science 2023 Jan 22; e2205289.
4.    Yetong Wang, Ru Yi Zhang, Yanni Pu, DanQi Wang, YanRen Wang , Xuemei Wu, Yujie Pan, Chen Luo, Guoping Zhao, ZheXue Quan*, Yan Zheng*. Sample collection, DNA extraction, and library construction protocols of the human microbiome studies in the International Human Phenome Project. Phenomics 2022. (Published Online)
5.    Chenhao Lin#, Zhonghan Sun#, Zhendong Mei#, Hailuan Zeng, Maying Zhao, Jianying Hu, Mingfeng Xia, Tao Huang, Chaolong Wang, Xin Gao, Yan Zheng*. The causal associations of circulating amino acids with blood pressure: A Mendelian randomization study. BMC Medicine. (2022) 20:414.
6.    Kang Yao, Yuxiang Dai, Juan Shen, Yi Wang, Li Jin, …, Shangyu Hong*, Yan Zheng*, Junbo Ge*. Exome sequencing identifies rare mutations of LDLR and QTRT1 conferring risk for early-onset coronary artery disease in Chinese. National Science Review. 2022 May 31;9(8): nwac102.
7.    Zhonghan Sun#, Zhi-Gang Song#, Chenglin Liu#, Shishang Tan#, Shuchun Lin, Jiajun Zhu, Fa-Hui Dai, Jian Gao, Jia-Lei She, Zhendong Mei, Tao Lou, Jiao-Jiao Zheng, Yi Liu, Jiang He, Yuanting Zheng, Chen Ding, Feng Qian, Yan Zheng*, Yan-Mei Chen*. Gut microbiome alterations and gut barrier dysfunction were associated with host immune homeostasis in COVID-19 patients. BMC Medicine. 2022 Jan 20;20(1):24.
8.    Zhendong Mei, Guo-Chong Chen, Jianying Hu, Chenhao Lin, Zhonghan Sun, Chenglin Liu, Xin Geng, Changzheng Yuan, Qibin Qi, Yan Zheng*. Habitual use of fish oil supplements, genetic predisposition, and risk of fractures: a large population-based study. Am J Clin Nutr. 2021 Sep 1;114(3):945-954
9.    Hailuan Zeng, Chenhao Lin, Sijia Wang*, Yan Zheng* & Xin Gao*. Genetically predicted body composition in relation to cardiometabolic traits: a Mendelian randomization study. Eur J Epidemiol. 2021 Nov;36(11):1157-1168.
10.    Huihui Guan#, Yanni Pu#, Chenglin Liu#, Tao Lou, Shishang Tan, Mengmeng Kong, Zhonghan Sun, Zhendong Mei, Qibin Qi, Zhe-Xue Quan, Guo-Ping Zhao, Yan Zheng*. Comparison of fecal collection methods on variation in gut metagenomics and untargeted metabolomics. mSphere. 2021 Oct 27;6(5): e0063621.
11.    Chenglin Liu#, Zhonghan Sun#, Shalaimaiti Shali#, Zhendong Mei, Shufu Chang, Hanjun Mo, Lili Xu, Yanni Pu, Huihui Guan, Guo-Chong Chen, Qibin Qi, Zhexue Quan, Ji Qi, Kang Yao, Yuxiang Dai*, Yan Zheng*, Junbo Ge. The gut microbiome and microbial metabolites in acute myocardial infarction. Journal of Genetics and Genomics. 2021 Dec 30; S1673-8527(21)00377-5.
12.    Yan Zheng*, Tao Huang, Tiange Wang, …, Lu Qi#. Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. Eur J Epidemiol. 2020 Jul;35(7):685-697.
13.    Zhendong Mei#, Xin Dong#, Yu Qian#, Dun Hong, Ziang Xie, Guanfeng Yao, An Qin, Songyan Gao, Jianying Hu, Liming Liang*, Yan Zheng*, Jiacan Su*. Association between the metabolome and bone mineral density in a Chinese population. EBioMedicine. 2020 Dec; 62:103111.
14.    Yan Zheng, Yanping Li, Ambika Satija, An Pan, Mercedes Sotos-Prieto, Eric Rimm, Walter C. Willett, and Frank B. Hu. Association of Changes in Red Meat Consumption with Total and Cause-Specific Mortality Among U.S. Women and Men: Two Large Prospective Cohort Studies. The BMJ. 2019 June 12;365:l2110.
15.    Yan Zheng, Sylvia H Ley, Frank B Hu. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. 2018 Feb;14(2):88-98.
16.    Yan Zheng, JoAnn E. Manson, Changzheng Yuan, Matthew H. Liang, Francine Grodstein, Meir J. Stampfer, Walter C. Willett, and Frank B. Hu. Associations of weight gain from early to middle adulthood with major health outcomes in later life. Journal of the American Medical Association (JAMA). 2017;318(3):255-269.