Joint PIs

Wei Hu

  • Position
    Joint PI
  • Email
    huw@fudan.edu.cn
  • Research Focus
    Microbiome & Agroecosystem
Position Joint PI Professor
Phone Email huw@fudan.edu.cn
Educational background Research Focus Microbiome & Agroecosystem
Work Experience
  • 2020.03 - present: Professor, Dean, School of Life Sciences, Inner Mongolia University

  • 2012.04 – present: Professor, Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University; Adjunct Professor at National Institute of Parasitic Diseases, Chinese Center for Diseases Control and Prevention.

  • 1996.07-2012.03: National Institute of Parasitic Diseases (NIPD), Chinese Center for Diseases Control and Prevention (China CDC) [former name: Institute of Parasitic Diseases, Chinese Academy of Preventive Medicine] Research Assistant (1996-1998), Assistant professor (1998-2003), Associate Professor (2003-2006), Professor (2006-2012).

  • 2002 PhD China Center for Diseases Control Pathology

  • 1996 M.S. Central China Normal University (China) Entomology

  • 1993 B.S.Central China Normal University (China) Biology

Research Interests

Professor Wei Hu is a parasitologist with broad interests in helminth biology, including development, genetics and evolution, as well as developing the new tools for parasitics diseases control. Her main interest is on Schistosoma japonicum’s invasion and development mechanism, population genetic variation and evolution features, rapid diagnostic method and drug development. Secondary interests include the biology of Echinococcus and other trematode. Recently, she broadened her interests to the agricultural microbiome which investigate the gut microbiota in cattles and sheep, as well as how the microbiota influences the growth, health and the productivity performance of the herds.

Selected Publications

1.    Luo F#, Yang W#, Yin M, Mo X, Pang Y, Sun C, Zhu B, Zhang W, Yi C, Li Z, Wang J, Xu B, Feng Z, Huang Y, Lu Y*, Hu W*.A chromosome-level genome of the human blood fluke Schistosoma japonicum identifies the genomic basis of host-switching. Cell Rep.  2022 ;39(1):110638.
2.    Luo F#, Yin M#, Mo X#, Sun C, Wu Q, Zhu B, Xiang M, Wang J, Wang Y, Li J, Zhang T, Xu B, Zheng H, Feng Z, Hu W*. An improved genome assembly of the fluke Schistosoma japonicum. PLoS Negl Trop Dis. 2019;13(8): e0007612.
3.    Li Q#, Zhao N#, Liu M, Shen HM, Huang L, Mo XJ, Xu B, Zhang XM, Hu W*. Comparative Analysis of Proteome-Wide Lysine Acetylation in Juvenile and Adult Schistosoma japonicum. Front Microbiol, 2017, 8: 2248
4.    Wang JP#, Yu Y#, Shen HM, Qing T, Zheng YT, Li Q, Mo XJ, Wang SQ, Li NN, Chai RY, Xu B, Liu M, Brindley PJ, McManus DP, Feng Z, Shi LM, Hu W* Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicum. Nat Commun.2017, 8:14693
5.    Li Q, Wang W, Zhao N, Li P, Xin Y, Hu W*, Identification and validation of a Schistosoma japonicum U6 promoter. Parasit Vectors.2017, 10(1):281
6.    Yin MB#, Zheng H#, Su J, Feng Z, McManus DP, Zhou X, Jin L and Hu W *. Co-dispersal of the blood fluke Schistosoma japonicum and Homo sapiens in the Neolithic Age. Sci Rep., 2015, 5: 18058
7.    Liu M,Ju C, Du XF, Shen HM, Wang JP, Li J, Zhang XM,Feng Z, Hu W*. Proteomic Analysis on Cercariae and Schistosomula in Reference to Potential Proteases Involved in Host Invasion of Schistosoma japonicum Larvae. J Proteome Res. 2015,14(11): 4623-4634
8.    Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium, Zhou Y#, Zheng H#, Liu F#, Hu W#, Wang ZQ#, Gang L#, Ren S#. The Schistosoma japonicum genome reveals features of host-parasite interplay. Nature. 2009, Jul 16; 460(7253):345-51.
9.    Liu F#, Cui SJ#, Hu W#, Feng Z, Wang ZQ, Han ZG*. Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum. Mol Cell Proteomics. 2009, Jun; 8(6):1236-51.
10.    Liu F#, Hu W#, Cui SJ#, Chi M, Fang CY, Wang ZQ, Yang PY, Han ZG*. Insight into the host-parasite interplay by proteomic study of host proteins copurified with the human parasite, Schistosoma japonicum. Proteomics. 2007 Feb;7(3):450-62
11.    Liu F#, Lu J#, Hu W#, Wang SY, Cui SJ, Chi M, Yang Q, Wang XR, Song HD, Xu XN, Wang JJ, Zhang XL, Zhang X, Wang ZQ, Xue CL, Brindley PJ, McMauns DP, Yang PY, Feng Z, Chen Z, Han ZG*. New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum. PLoS Pathog. 2006 Apr;2(4): e29.
12.    Hu W, Brindley PJ, McManus DP, Feng Z, Han ZG*. Schistosome transcriptomes: new insights into the parasite and schistosomiasis. Trends Mol Med. 2004 May;10(5):217-25.
13.    Hu W, Yan Q, Shen DK, Liu F, Zhu ZD, Song HD, Wang ZJ, Rong YP, Zeng LC, Wu J, Zhang X, Wang JJ, Xu XN, Wang SY, Fu G, Xu XR, Zhang XL, Wang ZQ, Brindley, PJ, McManus, DP, Xue CL, Feng Z, Chen Z, Han ZG*, Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource. Nat Genet. 2003 Oct; 35(2):139-47.