Joint PIs

2022.12-present, Fudan University Zhongshan Hospital, Department of Endocrinology, Associate Chief Physician

2021-present, Fudan University Zhongshan Hospital, Department of Endocrinology,Associate Researcher  

2019.07-2022.12, Fudan University Zhongshan Hospital, Department of Endocrinology, Attending Physician

2017.04-2019.07,  University of Michigan, Postdoc

2016.07-2017.04, Fudan University Zhongshan Hospital, Department of Endocrinology, Resident Physician  

2014.07-2016.07, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Resident Physician

2009.09-2014.07, Shanghai Jiao Tong University, Doctor of Medicine (Ph.D.) in Internal Medicine  

2004.09-2009.07, Southern Medical University, Bachelor of Medicine (B.M.) in Clinical Medicine

MAFLD and MASH

1. Liu C, Yi C, Fu W, Xiong X^*, Li J*. Metabolitin regulates intestinal fat absorption via lymphatic endothelial cells derived neurotensin. J Hepatol. 2023 Jul;79(1):e37-e39.

2. Liu C, Xiong X^*, Li J* Regulation of Atherosclerosis Development by Neurotensin Derived From Lymphatic Endothelial J.Arterioscler Thromb Vasc Biol. 2023 Sep;43(9):1743-1745.  

3. Xiong X, Kuang H, Liu T, Lin JD. A single‐cell perspective of the mammalian liver in health and disease. Hepatology. 2020 Apr;71(4):1467-1473.

4. Xiong X, Kuang H, Ansari S, Liu T, Gong J, Wang S, Zhao X, Ji Y, Li C, Guo L, Zhou L, Chen Z, Leon-Mimila P, Meng TC, Kurabayashi K, Opp J, Campos-Pérez F, Villamil-Ramírez H, Canizales-Quinteros S, Lyons R, Lumeng CN, Zhou B, Qi L, Huertas-Vazquez  A, Lusis AJ, Xu XZS, Li S, Yu Y, LI JZ, Lin JD. Landscape of intercellular crosstalk in healthy and NASH liver revealed by single-cellsecretome gene analysis. Mol Cell. 2019 Aug;75(3):644-660.

5. Liu B, Zhang Z, Hu Y, Lu Y, Li D, Liu J, Liao S, Hu M, Wang Y, Zhang D, Hu C, Xiong X^*, Li X^*. Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14. Proc Natl Acad Sci U S A. 2019 Oct ;116(43):21732-21738.

6. Xiong X, Wang Q, Wang S, Zhang J, Liu T, Guo L, Yu Y, Lin JD. Mapping the molecular signatures of diet-induced NASH and its regulation by the hepatokine Tsukushi. Mol Metab. 2019 Feb; 20:128-137.

7. Xiong X, Wang X, Lu Y, Wang E, Zhang Z, Yang J, Zhang H, Li X. Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice. J Hepatol. 2014 Apr; 60(4):847-54.

8. Zhao J^#, Xiong X^#, Li Y^#, Liu X, Wang T, Zhang H, Jiao Y, Jiang J, Zhang H, Tang Q, Gao X, Li X, Lu Y, Liu B, Hu C, Li X. Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A. Diabetes. 2018 May;67(5):818-830.

9. Lu Y^#, Xiong X^#, Wang X, Zhang Z, Li J, Shi G, Yang J, Zhang H, Ning G, Li X. Yin Yang 1 promotes hepatic gluconeogenesis through upregulation of glucocorticoid receptor. Diabetes. 2013.4, 62(4): 1064-1073.