Mingliang Fang-Fudan Microbiome Center

Joint PIs

Mingliang Fang

  • Position
    Joint PI
  • Email
    mlfang@fudan.edu.cn
  • Research Focus
    Exposome and microbiome
Position Joint PI Professor
Phone Email mlfang@fudan.edu.cn
Educational background Research Focus Exposome and microbiome
Work Experience

2022 - Present, Professor, Department of Environmental Science and Engineering, Fudan University

2016 - 2022, Assistant Professor, Department of Civil and Environmental Engineering, Nanyang Technological University, Singapore

2015 - 2016, Postdoctoral fellow, Metabolomics Center, The Scripps Research Institute (TSRI, La Jolla), USA

2011 - 2015, Duke University, Ph.D., Environmental Chemistry and Toxicology

2009 - 2011, Pohang University of Technology (POSTECH), Environmental Analytical chemistry, Master

2006 - 2009, China National Offshore Oil Tianjin Branch, EHS engineer

2002 - 2006, Bachelor DEGREE, Department of Environmental Engineering, Xi 'an Jiaotong University


Research Interests

The research interest is exposomics and environmental health, using systems biology methods to study the toxicity mechanism of pollutants. 

The findings were published as first or corresponding author in Nat Nanotechnol, Nat Chem Biol, Nat Water, PNAS, Environ Health Perspect, Environ Sci Technol, Anal Chem et al. more than 140 papers. Since 2021 he has been associate editor of Environmental Pollution, ESTL, Environ Int, ACS ES&T Water, RSC Environmental Science: Editorial board member of Processes & Impacts and other journals. He has won the introduction of overseas high-level talents, the 2023 ACS Chemical Research in Toxicology Young Scientist Award, the Youth Award of the Environmental Chemistry Congress, and the first "Xiaomi" Young Scholar. He was invited to report at the Gordon Research Conference, a well-known international association.

Selected Publications

1. Mengjing Wang, Qianqian Li, Meifang Hou, Louisa LY Chan, Meng Liu, Soo Kai Terd, Ting Dong, Yun Xia*, Sanjay H Chotirmalld, Mingliang Fang*. Inactivation of common airborne antigens by perfluoroalkyl chemicals modulates early-life allergic asthma. Proceedings of the National Academy of Sciences of the United States of America. 2021.

2. Beyer, B. A.#, Fang, M.# (Equal Contribution), Sadrian, B., Montenegro-Burke, J. R., Plaisted, W. C., Kok, B. P., ... & Lairson, L. L*. (2018). Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation. Nature Chemical Biology,  14(1), 22-28.

3. M Fang, L Hu, D Chen, Y Guo, J Liu, C Lan, J Gong, B Wang. “Exposome” in Human Health: Utopia or Wonderland? The Innovation, 100172, 2021

4. Fanrong Zhao, Li Li, Yue Chen, Yichao Huang, Tharushi Prabha Keerthisinghe, Agnes Chow, Ting Dong, Shenglan Jia, Shipei Xing, Benedikt Warth, Tao Huan and Mingliang Fang*. Risk-based Chemical Ranking and Generating a Prioritized Human Exposome Database. Environmental Health Perspective. 2021.

5. Liu, M., Jia, S., Dong, T., Zhao, F., Xu, T., Yang, Q., ... & Fang, M*. (2020). Metabolomic and Transcriptomic Analysis of MCF-7 Cells Exposed to 23 Chemicals at Human-Relevant Levels: Estimation of Individual Chemical Contribution to Effects. Environmental Health Perspectives.

6. Fang, M., Webster, T. F., Ferguson, P. L., & Stapleton, H. M*. (2015). Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. Environmental Health Perspectives,  123(2), 166-172. 

7. Pillai, H. K., Fang, M., Beglov, D., Kozakov, D., Vajda, S., Stapleton, H. M., ... & Schlezinger, J. J*. (2014). Ligand Binding and Activation of PPAR γ by Firemaster® 550: Effects on Adipogenesis and Osteogenesis in Vitro. Environmental Health Perspectives,  122(11), 1225-1232. 

8. Hoffman, K.#, Fang, M.# (Equal Contribution), Horman, B., Patisaul, H. B., Garantziotis, S., Birnbaum, L. S., & Stapleton, H. M. *(2014). Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. Environmental Health Perspectives,  122(9), 963-969. https://doi.org/10.1289/ehp.1308028.