高翔，山东大学微生物技术国家重点实验室教授、博士生导师。主持国家自然科学基金面上项目、国家重点研发计划国际合作等项目，入选国家高层次青年引进人才、获得“国家自然基金委优秀青年基金”和“山东省杰出青年基金”、山东省“青年泰山学者”等资助。课题组主要开展肠道菌，肠道病原菌与宿主之间相互作用的分子机制的研究，并以此为基础探索调控肠道稳态的新策略。相关成果以第一或通讯作者身份发表在Science、Nature、Cell、Nature Microbiology和Cell Host & Microbe等国际著名期刊。申请发明专利多项，授权5项。
Efficient interbacterial competitions and diverse defensive strategies employed by various bacteria play a crucial role in acquiring a hold within a dense microbial community. The human gut symbiont Bacteroides fragilis secretes a ubiquitin homologue (BfUbb) with unknown antibacterial mechanisms. In this presentation, we provide a comprehensive elucidation of the unprecedented mechanisms of BfUbb for interbacterial competition and explore its potential applications.
